Chitinase-like protein 1

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August undefined, 2024

WebBackground: Chitinase 3-like protein 1 (CHI3L1) is most likely a malignant tumor metastasis-associated gene. However, the functions of CHI3L1 in colon cancer cell proliferation and its cetuximab sensitivity are still unclear. We aimed to investigate the mechanism of CHI3L1 in promoting colon cancer cell proliferation and its sensitivity to … WebFollowing re-crystallization at neutral pH, the crystals were identified as the chitinase-like protein Ym1, expressed in organs of the lymphoreticular system, the lung, and distal stomach . Co-expression of Ym1 with Mac-1 and scavenger receptor pinpoints macrophages as its main producer .

Frontiers Chitinase-3 like-protein-1, matrix metalloproteinase -9 …

WebThe exaggerated expression of chitinase-like protein YKL-40, the human homologue of breast regression protein-39 (BRP-39), was reported in a number of diseases, including chronic obstructive pulmonary disease (COPD). However, the in vivo roles of YKL-40 in normal physiology or in the pathogenesis of … WebChitinase-3-Like Protein 1. YKL-40, a 40 kDa plasma protein, is the best-known protein from the CLPs group. YKL-40 lacks chitinolytic activity due to the mutation of glutamic acid to leucine in the chitinase-3-like catalytic domain. 27 The expression of YKL-40 was found in different mammalian organs and tissues (ie, ... ontario rent restrictions

Chitinase - an overview ScienceDirect Topics

WebChitinase 3-like 1 (CHI3L1) is a secreted glycoprotein that mediates inflammation, macrophage polarization, apoptosis, and carcinogenesis. The expression of CHI3L1 is strongly increased by various inflammatory and immunological conditions, including rheumatoid arthritis, multiple sclerosis, Alzheimer's disease, and several cancers. WebUrine chitinase 3-like. Background Acute kidney injury (AKI) is a frequently occurring syndrome in critically ill patients and is associated with worse outcomes. Biomarkers … ontario rent increase 2023 form

Chil1 chitinase-like 1 [ Mus musculus (house mouse) ]

Recombinant Human Chitinase 3-like 1 Protein, CF

WebPTHR22595:SF176 CHITINASE-LIKE PROTEIN 2 1 hit; PTHR22595 CHITINASE-RELATED 1 hit; PIRSF. PIRSF001060 Endochitinase 1 hit; Pfam. View protein in Pfam; … WebThe Quantikine Human CHI3L1 Immunoassay is a 4.5 hour solid phase ELISA designed to measure CHI3L1 in cell culture supernates, serum, plasma, and urine. It contains NS0 … ionia township ionia county miWebChitinase 3-like 1. Chitinase 3-like 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein member of the glycoside hydrolase 18 chitinase family that targets chitin but lacks enzymatic activity (Renkema et al., 1998). Although its physiologic function remains unknown, recent studies support a clear prognostic role for CHI3L1 in MS. ontario rent increase rules

"WebBackground: Chitinase 3-like 1. Chitinase 3-like 1 (CHI3L1), also called YKL-40 or human cartilage glycoprotein 39 (HCGP39), is a 39 kDa glycoprotein member of the glycosyl … " - Chitinase-like protein 1

Chitinase-like protein 1

Biomedicines Free Full-Text The lncRNAs/miR-30e/CHI3L1 Axis …

WebThe CLPs BRP-39/YKL-40 (also termed chitinase 3-like 1) inhibit oxidant-induced lung injury, augments adaptive Th2 immunity, regulates apoptosis, stimulates alternative … WebBackground and Objectives Multiple sclerosis (MS) is an autoimmune disease confined in the CNS, and its course is frequently subtle and variable. Therefore, predictive biomarkers are needed. In this scenario, we conducted a systematic review and meta-analysis to evaluate the reliability of chitinase 3–like 1 as a biomarker of MS. Methods Research …

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WebAug 16, 2024 · Chitinase-3-like 1 protein complexes modulate macrophage-mediated immune suppression in glioblastoma. J Clin Invest. 2024 Aug 16;131 (16):e147552. doi: 10.1172/JCI147552. WebChitinase-3-like protein 1 (CHI3L1) is a secreted glycoprotein characterized by its ability to regulate multiple biological processes, such as the inflammatory response and gene transcriptional signaling activation. Abnormal CHI3L1 expression has been associated with multiple neurological disorders and serves as a biomarker for the early ...

WebJan 25, 2024 · Acidic chitinase (Chia) has been implicated in asthma, allergic inflammations, and food processing. We have purified Chia enzymes with striking acid … WebMar 28, 2024 · chitinase-3-like protein 1, CGP-39, GP-39, YKL-40, breast regression protein 39, cartilage glycoprotein 39, chitinase 3-like 1. GeneRIFs: Gene References Into Functions. Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer.

WebChitinase 3-like 1. Chitinase 3-like 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein member of the glycoside hydrolase 18 chitinase family that targets chitin … WebChitinase-3-like protein 1 (YKL-40, also named human cartilage glycoprotein 39) is a mammalian glycoprotein related in sequence to family 18 of bacterial and fungal …

WebChitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. The name YKL-40 is derived from the three N …

WebObjective: To evaluate the classifier performance, clinical and biochemical correlations of cerebrospinal fluid (CSF) levels of the chitinase proteins Chitotriosidase-1 (CHIT1), Chitinase-3-like protein 1 (CHI3L1) and Chitinase-3-like protein 2 (CHI3L2) in amyotrophic lateral sclerosis (ALS). Methods: CSF levels of CHIT1, CHI3L1, CHI3L2, … ionia to st johns miWebNo chitinase activity. Essential for normal plant growth and development. Regulates cell expansion extent and differentiation at least in roots and hypocotyls. Prevents lignin … ontario rent lease agreement formWebChitinase-3-Like Protein 1. YKL-40, a 40 kDa plasma protein, is the best-known protein from the CLPs group. YKL-40 lacks chitinolytic activity due to the mutation of glutamic … ionia township hallWebSep 14, 2024 · Non-enzymatic chitinase-3 like-protein-1 (CHI3L1) belongs to glycoside hydrolase family 18. It binds to chitin, heparin, and hyaluronic acid, and is regulated by extracellular matrix changes ... ontario rent subsidy calculationWebAltogether, 14 chitinase-related genes (12 chitinase genes and 2 IDGFs) encoding 17 proteins were identified from the genome sequence of Ae. albopictus (Table (Table1). 1). These identified putative chitinase-like genes were assigned gene numbers according to the previously identified members of the other insect chitinase-like gene family to ... ontario rent rules for landlordsWebApr 6, 2024 · IntroductionPositive intracranial arterial remodelling is a dilated lesion of the large intracranial vessels; however, its pathogenesis is currently unknown. Some studies have identified chitinase-3 like-protein-1 (YKL-40) and matrix metalloproteinase (MMP)-9 as circulating inflammatory factors involved in positive vascular remodelling. Herein, we … ontario rent review boardWebJohansen and Carretta et al. found that COS exerted their anti-tumorigenic effects through the inhibition of YKL-40 (also known as chitinase-3-like 1 or Chi3L1), which is a conserved, secreted chitinase-like protein (CLP) found in elevated levels in many diseases, including cancer [126,127]. ionia township treasurer