WebCisplatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: nausea vomiting diarrhea hair loss loss in ability to taste food hiccups dry mouth, dark urine, decreased sweating, dry skin, and other signs of dehydration Some side effects can be serious. WebFeb 1, 2010 · Substitution of other platinum-based drugs can be effective following HSR, the most commonly used drug being cisplatin; 19 however, its increased toxicity, longer treatment times and 5-20% risk...
CARBOplatin - Cancer Care Ontario
Web1. Introduction. Among the second generation of platinum-containing drugs, carboplatin (CPT) is known as the most important one that is widely used in clinics for the treatment of cancer [].It is clinically proven to combat numerous types of malignancies such as lung, ovarian, head and neck, endometrial, esophageal cancer, etc. [].After crossing the cell … WebOct 5, 2014 · From the molecular perspective, cisplatin represents a perfect example of how a small alteration in chemical structure can significantly affect biological activity in target cell (Goodsell, 2006).As illustrated in Figure 2, cisplatin, carboplatin and oxaliplatin are composed of doubly charged platinum ion surrounded by four ligands; with the amine … d3162-a12 gs 2 manual
Carboplatin - Drug Information - Chemocare
WebApr 1, 2003 · Analysis of patients with epithelial ovarian cancer or fallopian tube carcinoma retreated with cisplatin after the development of a carboplatin allergy Gynecol Oncol, … WebSep 1, 2024 · Advanced Bladder Cancer. Cisplatin for injection has been administered at 50 mg/m 2 to 70 mg/m 2 intravenously per cycle once every 3 to 4 weeks. For heavily pretreated patients, an initial dose of 50 mg/m 2 per cycle repeated every 4 weeks is recommended. Other doses and combination in regimens have been used. WebJun 23, 2005 · As demonstrated in Table 2, hypersensitivity reactions appeared relatively late along the carboplatin treatment (mean, 9 treatments; range, 2–17 treatments).Seventeen (74%) patients developed their hypersensitivity reaction during the second or third line of carboplatin treatments after 1 or 2 prolonged no-treatment … bingo halls in glenrothes