Cisplatin and radiation therapy

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August undefined, 2024

WebFeb 16, 2016 · All patients were treated with high-dose cisplatin CCRT. The main outcome parameters were nephrotoxicity (defined as creatinine clearance grade 2 or more) and cumulative doses of cisplatin and radiation. Results: 133 patients (64%) completed all pre-planned courses of cisplatin. Nephrotoxicity was the main reason to discontinue the … WebThe drugs recommended for chemoradiation therapy include cisplatin, 5-fluorouracil (5-FU)/capecitabine, and taxol/docetaxel. Studies have reported that the mRNA expression level in tumor may predict drug efficacy. For example, excision repair cross-complementation 1 (ERCC1) is involved in the repair of DNA strand cleavage and damage.

Expanded Role for Immunotherapy to Treat Endometrial …

WebCisplatin-induced kidney toxicity is reviewed here. The use of cisplatin in patients with pre-existing kidney dysfunction and the kidney effects of the platinum analogs, carboplatin … WebSep 3, 1991 · After a preliminary dose-finding study involving 12 patients with advanced or locally recurrent head and neck cancer, 27 patients were treated on a phase II protocol, … side effects of injected steroids

Nephrotoxicity as a Dose-Limiting Factor in a High-Dose Cisplatin …

WebCisplatin is believed to augment the effects of radiation by inhibiting the repair of radiation-induced sublethal damage and by sensitizing hypoxic cells to radiation. 9,30 … WebDescription. This randomized phase III trial studies how well giving cisplatin and radiation therapy together with or without carboplatin and paclitaxel works in treating patients with … WebRadiation therapy, surgery, and chemotherapy are the three main treatments for head and neck cancer. Either radiation therapy, surgery, or both combined are typically used as the primary treatments with the goal of killing or removing the cancer. ... Drugs most commonly given in conjunction with radiation therapy are cisplatin (Platinol) and ... the pishon singers-tps

Radiation Therapy & Chemotherapy for Cervical Cancer

Clinical observation of gene expression-guided chemoradiation …

WebExternal-beam radiation therapy consists of x-ray treatments given daily for about five weeks. Low doses of chemotherapy drugs such as cisplatin (Platinol®) are used during this treatment to sensitize the cancer cells to radiation therapy. WebAug 26, 2024 · Although chemoradiation therapy (CRT) with cisplatin remains the standard treatment of patients with locally advanced cervical cancer (LACC), 40% of patients present with disease recurrence. … side effects of injectafer ironWebThe drugs recommended for chemoradiation therapy include cisplatin, 5-fluorouracil (5-FU)/capecitabine, and taxol/docetaxel. Studies have reported that the mRNA expression … side effects of injectafer

"WebJun 29, 2011 · Cisplatin at a dose of 100 mg/m 2 concurrent with radiation therapy is an intensive regimen, and adding a molecular-targeted agent might have resulted in the … " - Cisplatin and radiation therapy

Cisplatin and radiation therapy

A Phase III Trial of Adjuvant Chemotherapy Following …

WebYou might have cisplatin: every 3 or 4 weeks. once a week. every day over a 5 day period, every 3 to 4 weeks. You might have cisplatin on its own or in combination with other cancer treatments such as different chemotherapy drugs or radiotherapy. Your healthcare team will explain more about how you will have your treatment. WebCisplatin plus radiation therapy Advanced-stage squamous cell cancer of the head and neck remains a difficult therapeutic dilemma despite aggressive use of surgery and …

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WebMar 1, 2024 · Cumulative cisplatin dose during radiation therapy (RT) for SCCHN has a significant correlation with survival, 20 with 200 mg/m 2 suggested to be sufficient to achieve an additive effect with RT, irrespective of the method of administration. 21 On the basis of these results, treatment completion was defined as follows: for the 3-weekly arm ... WebHow Cisplatin + radiation chemotherapy is given and possible side effects. Cisplatin + radiation for the treatment of Head and Neck Cancer. Cisplatin + Radiation is used …

Webwww.ncbi.nlm.nih.gov WebJan 27, 2024 · Chemotherapy drugs, such as cisplatin or carboplatin, may be given at the same time as radiation therapy. Giving chemotherapy at the same time as radiation therapy helps the radiation therapy work better. For information about these treatments, see Cervical Cancer Treatment. Treatment of stage IVB cervical cancer

WebRadiotherapy (RT) was given concurrently with cisplatin and etoposide. G-CSF was given as primary or secondary prophylaxis or as a therapeutic measure during an episode of febrile neutropenia according to local protocols. Common terminology criteria for adverse events (CTCAE) v3.0 was used to record toxicity. ... Lung Neoplasms / therapy* Male ... WebFeb 16, 2024 · radiation treatment to your brain; liver disease; or. if you have had a severe allergic reaction to similar cancer drugs such as carboplatin or oxaliplatin. A child treated with cisplatin may need a hearing test before receiving the first dose. Using cisplatin may increase your risk of developing leukemia. Ask your doctor about your individual ...

WebJun 22, 2024 · Chemotherapy (chemo) work by a variety of different mechanisms, but their general effect is to slow or stop the growth of cancer cells, which divide and grow quickly. The most common ways chemo may be given include intravenous (IV), injection (shot) or by mouth like a pill. These methods circulate the medicines throughout the body.

WebEffect of the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation Therapy for Patients With Esophageal Cancer: The NRG Oncology RTOG 0436 Phase 3 … the pish pad storeWebA randomized trial of liposomal paclitaxel plus cisplatin as first‐line therapy for advanced non‐small cell lung cancer. Zhongguo Fei Ai Za Zhi. 2012; 15 ... Zhang W, Yan C, Zhang T, et al. Addition of camrelizumab to docetaxel, cisplatin, and radiation therapy in patients with locally advanced esophageal squamous cell carcinoma: a phase 1b ... side effects of injected insulinWebAug 14, 2024 · The U.S. Food and Drug Administration has previously approved cetuximab with radiation for patients with head and neck cancer, including oropharyngeal cancer. Cetuximab with radiation is an accepted standard of care, especially for patients who cannot tolerate cisplatin. the pi shopWebApr 1, 2024 · Ou X, Zhou X, Shi Q, Xing X, Yang Y, Xu T, Shen C, Wang X, He X, Kong L, Ying H, Hu C. Treatment outcomes and late toxicities of 869 patients with nasopharyngeal carcinoma treated with definitive intensity modulated radiation therapy: new insight into the value of total dose of cisplatin and radiation boost. Oncotarget. 2015 Nov … side effects of injecting methWebFeb 1, 2024 · James RD, Glynne-Jones R, Meadows HM, et al. Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a ... side effects of injectable testosteroneWebThe cytotoxic action of ionizing radiation can be increased by cis-platinum (CDDP) and its derivates. ... [Cisplatin and radiotherapy] Strahlentherapie. 1985 Jun;161(6):367-73. ... side effects of injecting heroinWebFeb 16, 2016 · All patients were treated with high-dose cisplatin CCRT. The main outcome parameters were nephrotoxicity (defined as creatinine clearance grade 2 or more) and … the pisikian law firm