Witryna25 wrz 2024 · The IMpower133 trial evaluated the efficacy and safety of adding atezolizumab or placebo to first-line treatment with carboplatin and etoposide in patients with extensive-stage small-cell lung... Witryna7 mar 2024 · Interventional (Clinical Trial) Actual Enrollment : 453 participants: Allocation: Randomized: Intervention Model: Parallel Assignment: Masking: Double (Participant, Care Provider) Primary Purpose: Treatment: Official Title: A Phase III, Double-Blinded, Multicenter, Randomized Study Evaluating the Efficacy and Safety of …
Asco 2024 – adjuvant lung cancer beckons for Tecentriq
Witryna20 lis 2024 · Sub-group analyses of IMpower010 showed that the DFS advantage of atezolizumab was greater in patients with PD-L1 >50% (HR 0.43) compared with those with PD-L1 1–49% (HR of 0.87). On the basis of these results, it is likely that in Asia we will refine the target to patients who have PD-L1 >50%.” WitrynaThis randomized clinical trial evaluates the effect of postoperative radiotherapy on survival and safety in patients with pIIIA-N2 non–small cell lung cancer af [Skip to Navigation] ... particularly given the encouraging results of the recently presented IMPOWER-010 study3. As immunotherapy becomes integrated into the treatment … opening braw files
eUpdate – Early and Locally Advanced Non-Small-Cell Lung …
Witryna5 lip 2024 · The IMpower 010 study is a phase III, global, multicenter, open-label, randomized study to compare the efficacy and safety of 16 atezolizumab treatment cycles, compared to best supportive care, for patients with stage IB–IIIA NSCLC after resection and adjuvant chemotherapy. WitrynaPhase II clinical trials have shown promising results, and prospective phase III trials are currently underway. The role of adjuvant immunotherapy with checkpoint inhibitors is unclear and remains the subject of numerous prospective studies. ... IMpower-010 (NCT02486718) III 1280 больных 1Ва-ША ст. после радикальной ... WitrynaImpower-010 scores on an apparently approvable endpoint, but the effect in all-comers is illusory, researchers reckon. Roche’s Tecentriq looks on track to become the first immunotherapy to be approved for the perioperative treatment of non-small cell lung cancer, data from the adjuvant study Impower-010 just unveiled at the virtual opening boxes of hockey cards