Web13 Aug 2015 · To remedy this lack of Lassa virus genome information, the authors collected clinical samples from patients in Sierra Leone and Nigeria between 2008 and 2013. From these and other sources they determined the sequences of 183 Lassa virus genomes from humans, 11 viral genomes from M. natalensis , and two viral genomes from … Web301 Moved Permanently. nginx
UniProt
Web10 Oct 2012 · Arenaviruses have a bisegmented negative-strand RNA genome, which encodes four viral proteins: GP and NP by the S segment and L and Z by the L segment. These four viral proteins possess multiple functions in infection, replication and release of progeny viruses from infected cells. The small RING finger protein, Z protein is a matrix … WebOverview. Lassa fever may be transmitted from either infected animals (typically rodents) or humans following exposure to body fluids and excretions/secretions from the respiratory tract or GI tract. Following transmission, Lassa virus infects the endothelium and replicates intracellularly using an L-polymerase enzyme and nucleocapsid protein ... hampton court palace concert tickets
Innovative genomics tool guides response to Lassa fever outbreak
Web17 Oct 2024 · Phylogenetic analysis of the full data set shows that Lassa virus genomes cluster geographically with the persistence of two main genetically distinct lineages. Lineage II, which includes 93%... Web4 Jan 2024 · Metagenomic classification using the Centrifuge software system ( 13) identified 0.10% of reads from sample 110 as originating from hepatitis A virus, providing 74% genome coverage at 20-fold depth. LASV accounted for 0.83% of reads in the same sample, providing 96% genome coverage. WebLassa virus, an Old World arenavirus (family Arenaviridae), is the etiological agent of Lassa fever, a severe human disease that is reported in more than 100,000 patients ... The genome of arenaviruses consists of two single-stranded RNA segments, small (S) and large (L). Both genomic segments have an ambisense gene organization and encode two ... burter sh figuarts